Dr Khanyisile and Dr Ziyanda Ndebele
4 min read
08 Oct
08Oct


What a whirlwind! We're still buzzing from the energy of the official Wegovy launch event we attended right here in beautiful Cape Town on Saturday, August 16, 2025. It wasn't just another corporate meeting—it was a truly unforgettable day filled with learning, connection, and, of course, absolutely delicious (and perfectly portioned!) food.

Complications of Obesity:


The venue was stunning, the Novo Nordisk team was top-notch, and the excitement for bringing this groundbreaking treatment to South Africans was palpable. More than the great views and the fun networking, the best part was diving deep into the science behind Wegovy and understanding exactly why the global health community is talking about it so much.


So, What Exactly is Wegovy and How Does It Work?

Wegovy is a once-weekly injectable medicine used alongside a reduced-calorie diet and increased physical activity for chronic weight management. Its active ingredient is called semaglutide, the same active ingredient found in Ozempic — but Wegovy is specifically designed and dosed for weight management rather than diabetes. It works by mimicking a natural hormone in your body called GLP-1 (glucagon-like peptide-1).


Think of GLP-1 as your body’s internal signal manager for food:

1. Taming the Appetite: GLP-1 targets the parts of your brain responsible for hunger and food intake. It basically turns down the volume on constant food thoughts (what some people call "food noise"), helping you feel less hungry.

2. Slowing Things Down: It also slows down how quickly food leaves your stomach. This means you feel fuller, sooner, and that feeling lasts longer—a huge game-changer for controlling portions. Essentially, Wegovy helps reset your body's natural hunger cues, making it easier to stick to the healthy lifestyle changes needed for long-term success.


The Science Speaks: What the Studies Tell Us

The presentations from the clinical experts in Cape Town really hammered home the strong evidence behind Wegovy. This isn't just about small, temporary changes; the results from the global clinical trials (part of the major STEP program) are remarkable:

Significant Weight Loss: In clinical studies, adults without diabetes who used Wegovy (2.4 mg once-weekly dose) in conjunction with diet and exercise achieved an average weight loss of approximately 15% of their initial body weight over 68 weeks. To put that in perspective, participants on placebo (with diet/exercise alone) lost about 2.4%.

Beyond the Scale: Cardiovascular Benefits: Perhaps the most exciting recent news, heavily discussed at the launch, comes from the SELECT trial. This study showed that in adults with known heart disease and excess weight, Wegovy demonstrated a significant 20% lower risk of major cardiovascular events like heart attack, stroke, or cardiovascular death, regardless of how much weight they lost. This suggests that the benefits of the medication go far beyond just looking good—they directly improve heart health.

  • Wegovy isn’t a “magic shot” — it works best when paired with balanced nutrition, exercise, and lifestyle changes.
  • Beyond weight loss, people also saw improvements in blood pressure, cholesterol, and energy levels.
  • It can be especially helpful for those who have struggled with obesity for years, giving them a safe and science-backed option.


Our Takeaway

Let’s just say - The launch was fantastic and Cape Town showed off. Between the ocean views, good company, and inspiring speakers, the event had such an energizing, positive energy. We connected with other healthcare professionals, learned about the science behind Wegovy, and got a fresh boost of motivation to help our patients reach their goals safely. We walked away from the launch not only with new medical insights but also a renewed excitement for empowering our patients on their weight and wellness journeys.


The key message? 

Wegovy is an important tool, approved for use in adults living with obesity, or those who are overweight with a related health condition (like high blood pressure or high cholesterol), that should always be used alongside a commitment to a reduced-calorie diet and increased physical activity. Wegovy represents more than just a medication — it’s a tool for transformation when used responsibly, with the right guidance and support. We're incredibly excited to see the positive impact this will have now that it’s officially launched here in South Africa!

If you’ve been curious about medical weight loss options or want to know if Wegovy might be right for you, chat to our team at Health Life Aesthetics. We’re here to help you find the safest, most sustainable path to your healthiest self.


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